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With publicity to doses with the WNT agonist CHIR99021, the elongation of hPSC aggregates and the development of NMP cells may be observed, and also the presence in the mesoderm and neuroectoderm. Neural tubes have been also induced in mouse TLSs designed by Veenvliet et al. when cultured in a 5% development aspect-diminished Matrigel ailment, alon
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